Sensitization of interferon-γ induced apoptosis in human osteosarcoma cells by extracellular S100A4
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چکیده
منابع مشابه
Molecular Mechanisms of Luteolin Induced Growth Inhibition and Apoptosis of Human Osteosarcoma Cells
Luteolin is a flavone in medicinal plants as well as some vegetables and spices. It is a natural anti-oxidant with less pro-oxidant potential but apparently with a better safety profile. The purpose of this study was to investigate the molecular mechanism of luteolin-mediated apoptosis of MG-63 human osteosarcoma cells. MTT assay kit was employed to evaluate the effects of luteolin on MG-63 cel...
متن کاملMolecular Mechanisms of Luteolin Induced Growth Inhibition and Apoptosis of Human Osteosarcoma Cells
Luteolin is a flavone in medicinal plants as well as some vegetables and spices. It is a natural anti-oxidant with less pro-oxidant potential but apparently with a better safety profile. The purpose of this study was to investigate the molecular mechanism of luteolin-mediated apoptosis of MG-63 human osteosarcoma cells. MTT assay kit was employed to evaluate the effects of luteolin on MG-63 cel...
متن کاملInvolvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis
The synthetic cannabinoid WIN 55,212-2 is a potent cannabinoid receptor agonist with anticancer potential. Experiments were performed to determine the effects of WIN on proliferation, cell cycle distribution, and programmed cell death in human osteosarcoma MG63 and Saos-2 cells. Results show that WIN induced G2/M cell cycle arrest, which was associated with the induction of the main markers of ...
متن کاملmolecular mechanisms of luteolin induced growth inhibition and apoptosis of human osteosarcoma cells
luteolin is a flavone in medicinal plants as well as some vegetables and spices. it is a natural anti-oxidant with less pro-oxidant potential but apparently with a better safety profile. the purpose of this study was to investigate the molecular mechanism of luteolin-mediated apoptosis of mg-63 human osteosarcoma cells. mtt assay kit was employed to evaluate the effects of luteolin on mg-63 cel...
متن کاملMechanism of Osteosarcoma Tumorigenesis by S100A4
INTRODUCTION Osteosarcoma (OS) is the most common primary malignancy of bone in children and young adults. Although current treatment protocols involve both wide local resection and chemotherapy, the average fiveyear disease free survival is only 50-65%. Despite significant advances in surgical techniques and chemotherapeutic regimens over the past few decades, there has been minimal improvemen...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2004
ISSN: 1471-2407
DOI: 10.1186/1471-2407-4-52